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Beilstein J. Org. Chem. 2007, 3, No. 40, doi:10.1186/1860-5397-3-40
Graphical Abstract
Scheme 1: Michael-type addition of 5-substituted uracil derivatives to 2-hydroxyethyl acrylate.
Scheme 2: Synthesis of the model ester-conjugated acyclic nucleoside.
Figure 1: Protons assignment in NMR spectrum of the model ester-conjugated nucleoside (4).